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Methoxyisoflavone, marketed as Methoxy ______ (you fill in the blank) is the latest bodybuilding craze. It often marketed, "as good as anabolic steroids without the androgenic or liver damaging side effects." This statement is misleading, because methoxyisoflavone is not a steroid nor does it act like a steroid. However, taking methoxyisoflavone--especially in a stack with ecdysterone (shown to increase nitrogen retention) and protein--can decrease cortisol levels, increase protein synthesis, and improve overall recovery from exercise. You build muscle and endurance.
Methoxyisoflavone and its cousin, Ipriflavone, are non-hormonal, anabolic (muscle building) / anti-catabolic (muscle breakdown) compounds developed in the 1970s by the Hungarian pharmaceutical company, Chinoin. Chinoin's research was so significant that it was able to achieve the difficult task of getting a U.S. patent on the flavones for their ability to increase weight gain and increase anabolism. The patent expired in 1997, and within the last few years sports nutrition companies have been developing products using these compounds.
The marketing hype relies upon the original research done by Chinoin in the 1970s. In one study, cattle, pigs, rabbits and poultry that were given Ipriflavone-enriched feed at a dosage of 2 grams per 100kg increased in lean body mass at an incredible 7% to 20%. The animals were dissected, revealing that they had grown more muscular with no negative impact on testosterone, testicular shrinkage, or aromatization (chemical stability)--which are all possible anabolic steroid side effects. In the human studies, wasting patients given Ipriflavone increased in lean body weight by 2 to 3 kilograms in merely a few weeks.
In similar studies, Methoxyisoflavone was shown to be more anabolic than both Ipriflavone and anabolic steroids. In both animal and human studies, lean body mass and vitality increased significantly within 30 days, while producing no androgenic (male sex hormone) effects and no endocrine (hormone secreting) tissue alteration. Cortisol levels were reduced in wasting patients, while phosphorus, calcium, potassium, and nitrogen (needed for muscle building) levels increased considerably. Since Methoxyisoflavone and Ipriflavone utilize different metabolic pathways, it has been conjectured that stacking the two together can increase the anabolic action.
For more information see:
http://www.abetterbody.com/get-fit/fitness_Articles/mx7_brian_b_article.html
http://www.bodybuilding.com/store/methoxy.html
http://www.eas.com/products/product_select.asp?ProductName=117
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